Pancreas Question 14 September 17, 2025 rmalaca1 Please wait... 1. What is the most likely genetic abnormality in a tumor that presents as a large, soft, tan, friable nodule within a dilated main pancreatic duct, and shows complex, branching papillae lined by cells with abundant granular eosinophilic cytoplasm and foci of cribriform structures?A.KRAS mutationsB.SMAD4 mutationsC.TP53 mutationsD.PRKACA and PRKACB gene fusionsE.CTNNB1 mutations Loading...